OPTIMAL DESIGN OF THE ANNUAL INFLUENZA VACCINE by
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Optimizing the process of inactivating influenza virus subtype H9N2 by formalin in the production of killed avian influenza vaccine
Avian influenza is one of the most important diseases in avian industry, which also threats human population. Thus, vaccination is necessary for controlling this viral disease. In this study, killed vaccine of avian influenza subtype H9N2 and formalin solution (for virus inactivation) were used. It is necessary to study the effect of different factors such as formalin concentration, as well as ...
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Background and Aims: Influenza vaccine production process is time-consuming with little-to-no cross-protection which requires annual adjustment. The construction of a universal vaccine to deal with the pandemics and epidemics which occasionally threat human population is the aim of many researches worldwide. Today, influenza vaccines are mostly against two major antigenic proteins, hemagglutini...
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Background and Aims: Influenza is one of the main respiratory infections of humans, responsible for 300,000–500,000 annual deaths world-wide. Vaccination is one of the best ways to prevent infections including influenza. Influenza virosomes are virus-like particles, which retain the cell binding and membrane fusion properties of the native virus, but lack the ribonucleoprotein (RNP). A vi...
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Objectives: Influenza disease considered to be more sever and complicated in old age persons, because immune response diminish in this group. This disease is one of the main causes of mortality in elder people. The prevalence of influenza disease in elderly are living in nursing home is more in compare if they dwell in community. We studied the effect of influenza vaccine on the incidence and n...
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Background and aims: Increasing rate of reference of Influenza patients to hospitals besides recent H1N1 pandemic experiences and also threats of incoming Avian flu denote to the importance and necessity of Hospitals' staff annual vaccination against influenza. Methods: In this cross sectional and questionnaire based study 276 of shiraz general hospitals' personnel were selected b...
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